medical marijuana cbd

Medical marijuana cbd

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Murnion, B. “Medical Cannabis.” Aust Prescr. 2015 Dec; 38(6): 212–215.
<http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674028/>

At the time this article was written, 23 states have legalized medical marijuana with varying restrictions. However, it is classified as a Schedule I substance by the Federal Drug Administration (FDA) and thus is illegal at the Federal level. In most states with legal medicinal marijuana, a prescription, authorization, or medical recommendation is required, and a card or license is issued. This allows a person to buy medical marijuana.

How do you get medical marijuana?

Sexton, M., et al. “A Cross-Sectional Survey of Medical Cannabis Users: Patterns of Use and Perceived Efficacy.” (Under Review 2016: Cannabis and Cannabinoid Research).

More research has been conducted on the compound CBD. Medical CBD is anti-inflammatory, anticonvulsant, antioxidant, neuroprotective, and anxiolytic, antipsychotic, and anti-emetic. The CBD compound in medical marijuana appears to be neuroprotective in Huntington’s, Parkinson’s, and Alzheimer’s disease, fetal hypoxia, and other neurodegenerative conditions and movement disorders.

Allsop, DJ., et al. “Nabiximols as an agonist replacement therapy during cannabis withdrawal: a randomized clinical trial.” JAMA Psychiatry 2014;71:281-91.

What research is being done for medical marijuana?

Fernández-Ruiz, J. et al. “Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid.” Br J Clin Pharmacol. 2013 Feb;75(2):323-33.

THC:CBD: Nabiximols (Sativex) is a specific plant extract with an equal ratio of THC: CBD. It is approved as a drug in the UK and elsewhere in Europe for the treatment of multiple sclerosis, spasticity, neuropathic pain, overactive bladder, and other indications.

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Medical marijuana cbd

A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So, you cannot be sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other unknown elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.

Outside of the US, the prescription drug Sativex, which uses CBD as an active ingredient, is approved for muscle spasticity associated with multiple sclerosis and for cancer pain. Within the US, Epidiolex is approved for certain types of epilepsy and tuberous sclerosis.

Animal studies, and self-reports or research in humans, suggest CBD may also help with:

Is CBD safe?

Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer or COVID-19, which it is not. We need more research but CBD may prove to be a helpful, relatively non-toxic option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies, we can’t pinpoint effective doses, and because CBD currently is typically available as an unregulated supplement, it’s hard to know exactly what you are getting.

CBD is readily obtainable in most parts of the United States, though its exact legal status has been in flux. All 50 states have laws legalizing CBD with varying degrees of restriction. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. In 2018, the Farm Bill made hemp legal in the United States, making it virtually impossible to keep CBD illegal – that would be like making oranges legal, but keeping orange juice illegal.

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CBD comes in many forms, including oils, extracts, capsules, patches, vapes, and topical preparations for use on skin. If you’re hoping to reduce inflammation and relieve muscle and joint pain, a topical CBD-infused oil, lotion or cream – or even a bath bomb — may be the best option. Alternatively, a CBC patch or a tincture or spray designed to be placed under the tongue allows CBD to directly enter the bloodstream.

How can CBD be taken?

People taking high doses of CBD may show abnormalities in liver related blood tests. Many non-prescription drugs, such as acetaminophen (Tylenol), have this same effect. So, you should let your doctor know if you are regularly using CBD.

CBD, or cannabidiol, is the second most prevalent active ingredient in cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, a cousin of marijuana, or manufactured in a laboratory. One of hundreds of components in marijuana, CBD does not cause a “high” by itself. According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”