Procedures: Dogs were randomly assigned to a CBD (n = 12) or placebo (14) group. The CBD group received CBD-infused oil (2.5 mg/kg [1.1 mg/lb], PO) twice daily for 12 weeks in addition to existing antiepileptic treatments, and the placebo group received noninfused oil under the same conditions. Seizure activity, adverse effects, and plasma CBD concentrations were compared between groups.
Design: Randomized blinded controlled clinical trial.
Results: 2 dogs in the CBD group developed ataxia and were withdrawn from the study. After other exclusions, 9 dogs in the CBD group and 7 in the placebo group were included in the analysis. Dogs in the CBD group had a significant (median change, 33%) reduction in seizure frequency, compared with the placebo group. However, the proportion of dogs considered responders to treatment (≥ 50% decrease in seizure activity) was similar between groups. Plasma CBD concentrations were correlated with reduction in seizure frequency. Dogs in the CBD group had a significant increase in serum alkaline phosphatase activity. No adverse behavioral effects were reported by owners.
Objective: To assess the effect of oral cannabidiol (CBD) administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with idiopathic epilepsy.
Animals: 26 client-owned dogs with intractable idiopathic epilepsy.
Conclusions and clinical relevance: Although a significant reduction in seizure frequency was achieved for dogs in the CBD group, the proportion of responders was similar between groups. Given the correlation between plasma CBD concentration and seizure frequency, additional research is warranted to determine whether a higher dosage of CBD would be effective in reducing seizure activity by ≥ 50%.
The first thing that you should do, especially if your pet is receiving treatment for any medical issues, is to speak to your veterinarian. Because you work with your veterinarian as a team for your pet’s health, you should both be on the same page. Find out what your vet thinks about using CBD oil and get his permission first.
Canine CBD oil is an extracted from hemp plants. It is one of over 100 cannabinoids found in cannabis plants (hemp is in the cannabis family). CBD is short for cannabidiol. Cannabidiol, or CBD, is equally as familiar to most people as tetrahydrocannabinol THC is.
You also will want to do some research. As fast as you learn about CBD dog, there is new information coming forth. The sheer speed at which research is coming out is mind-boggling. It’s essential to learn as much about it as you can, what is a suitable type of oil, what is the best CBD oil for dogs, and which delivery method you feel is best for your pet. There are treats, edibles, drops, and more that you can choose to give doses to your dog.
Pet owners and their pets alike all have an endocannabinoid system. Within the ECS, there are endocannabinoid receptors which bind to CBD molecules found in CBD products. Without endocannabinoid receptors, a doga wouldn’t be able to break down CBD oils.
How Can I Get a Hold of CBD Oil?
Speaking of Colorado, many studies have been conducted regarding CBD for dogs at Colorado State University. Awhile back, researchers at Colorado State University, including Dr. Stephanie McGrath, started looking into the effects of CBD on canine seizures in dogs. Currently, researchers are continuing to conduct research in an attempt to better understand how CBD is absorbed by the bodies of cats and dogs.
Tetrahydrocannabinol THC is the psychoactive compound found in marijuana that is responsible for the head high experienced from using it. But CBD products derived from a hemp plant are free of toxins, psychoactive properties, and other high related side effects. Hemp is free from THC because the hemp plant itself contains less than 0.3% of THC in the first place.
Dog seizures and epilepsy in general are scary for anyone to witness, but when it is your dog, it is emotionally wrecking to watch. It leaves you feeling helpless and distraught, which is the opposite of how we like to feel when it comes to our babies. We want them to know they are safe with us and that we will take care of them, no matter what.
The Many Treatment Options for Dogs with Epilepsy
The health of your dog is all that matters, and it’s important to get their health under control, which CBD treats, oils, and supplements can help with! Dogs should be at least 12 weeks old before taking treats or other products. Since seizures stem from the brain, and CBD affects the brain, your dog’s vet will want to make sure your dog’s brain is developed enough before taking it.
Published at: June 4, 2021
One of the things to keep in mind about anticonvulsant pharmaceuticals is that once a dog goes on them, most veterinarians are likely to recommend that they stay on them for life. In cases of idiopathic epilepsy, where the seizures are short and infrequent and more serious causes have been ruled out, you and your vet may decide not to put your dog on an anticonvulsant medication and instead, deal with occasional seizures when they occur.
• List all the active and inactive ingredients found in each of their CBD pet products. This includes flavors, carrier oils and the exact milligrams (mg) of CBD.
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Research on CBD and Epilepsy
• Idiopathic Epilepsy: The most common type of seizure activity in dogs, particularly dogs between six months and six years of age. “Idiopathic” means that after using diagnostic testing to rule out possible conditions, there is no identifiable cause for the seizures. It is thought that at least some of these idiopathic seizures are inherited conditions, as some breeds, including Boxers and other Bully types, seem to have them more frequently.