In addition, our bodies consist of several other receptor proteins that work in the ECS, like GPR3, GPR6, TRPV1, and TRPV2. CBD binds to all of these, and many of its pain-relieving and anti-inflammatory effects may occur through these pathways.
We will explore this in more detail a little later. Understanding cannabidiol is the key to understanding how CBD products work and why the compound has captured the attention of so many scientists.
You can also apply CBD topically. Skin and beauty products infused with CBD are all-natural and thought to be very good for the skin. Many athletes like using CBD salves for joint and muscle pain either before or after workouts. It helps to soothe aches and pains from vigorous exercise.
CBD Product Types
On the other hand, CBD is associated with promoting an overall sense of calm. It may also help to bring the body back into balance.
If you want to know if the CBD is sourced from cannabis or hemp, you will need to check the product label or inquire with the company. All reputable and trustworthy CBD companies publish certificates of analysis (COA) or lab reports for their products.
CBD: What Is It?
More importantly, CBD could have numerous therapeutic benefits. These include anti-inflammatory, pain-relieving, anti-anxiety, seizure-suppressant, and analgesic properties.
CBD interacts directly with numerous components in the body and the central nervous system. A few of these are components of the endocannabinoid system (ECS).
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer or COVID-19, which it is not. We need more research but CBD may prove to be a helpful, relatively non-toxic option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies, we can’t pinpoint effective doses, and because CBD currently is typically available as an unregulated supplement, it’s hard to know exactly what you are getting.
CBD comes in many forms, including oils, extracts, capsules, patches, vapes, and topical preparations for use on skin. If you’re hoping to reduce inflammation and relieve muscle and joint pain, a topical CBD-infused oil, lotion or cream – or even a bath bomb — may be the best option. Alternatively, a CBC patch or a tincture or spray designed to be placed under the tongue allows CBD to directly enter the bloodstream.
Outside of the US, the prescription drug Sativex, which uses CBD as an active ingredient, is approved for muscle spasticity associated with multiple sclerosis and for cancer pain. Within the US, Epidiolex is approved for certain types of epilepsy and tuberous sclerosis.
Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level of blood thinning and other medicines in your blood by competing for the liver enzymes that break down these drugs. Grapefruit has a similar effect with certain medicines.
How can CBD be taken?
CBD, or cannabidiol, is the second most prevalent active ingredient in cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, a cousin of marijuana, or manufactured in a laboratory. One of hundreds of components in marijuana, CBD does not cause a “high” by itself. According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”
The Farm Bill removed all hemp-derived products, including CBD, from the Controlled Substances Act, which criminalizes the possession of drugs. In essence, this means that CBD is legal if it comes from hemp, but not if it comes from cannabis (marijuana) – even though it is the exact same molecule. Currently, many people obtain CBD online without a medical marijuana license, which is legal in most states.
Animal studies, and self-reports or research in humans, suggest CBD may also help with:
Is CBD safe?
A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So, you cannot be sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other unknown elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.
CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and, in some cases, stop them altogether. Epidiolex, which contains CBD, is the first cannabis-derived medicine approved by the FDA for these conditions.