cbd oil als

Cbd oil als

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Cbd oil als

Furthermore, marijuana sales are not currently allowed in a variety of jurisdictions in the USA, making it all the more difficult for doctors to recommend it as a useful option to assist with ALS symptoms.

Another potential benefit of CBD for ALS patients is its ability to regulate the immune system and quell inflammation. Experts have suggested that immune dysfunction may contribute to the development of ALS and research has shown that people with the condition often have excessive levels of inflammation.

Doctors often recommend ALS support group plans that work to improve the mental health of sufferers. It is also beneficial for patients as they can connect to others with the same diagnosis.

However, CBD may address the side effects of drugs such as Riluzole, allowing patients to have less stress and discomfort. CBD may assist in making patients’ lives easier, allowing doctors and specialists to concentrate on long-range options and care.

Why Not Just Smoke Regular Marijuana?

ALS, also known as Lou Gehrig’s disease, is a degenerative disorder. Researchers named this disorder after the famous baseball legend Lou Gehrig, who was the first to be formally diagnosed with the condition. Characteristics of this disorder include gradually worsening muscle control and strength, which can eventually involve the inability to speak or swallow.

The report demonstrated that CBD and Riluzole delayed the progression of the disease in a patient recently diagnosed with ALS. It improved symptoms such as muscle weakness and difficulties with speech and swallowing for approximately 12 months.

ALS patients may now use CBD oil to mitigate or reduce their symptoms as it is readily available in many places. Studies show that there is great promise in how people can benefit from CBD.

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So Is CBD Oil Only Useful as a Co-Medication?

Although there is currently no evidence that CBD can reduce inflammation in ALS, specifically, it may well have positive effects. While CBD seems to be a worthwhile option, some might be wondering why patients use CBD oil rather than whole-plant, medical marijuana. , In fact, there are a few reasons why some experts don’t recommend regular cannabis for treating ALS.

Over the years, more and more researchers have conducted studies to show CBD’s efficacy as a way to help those with ALS.

Cbd oil als

TSQM-9, Question 6 (convenience) – administration of THC:CBD as instructed: 84% of patients (n = 27) considered the administration of THC:CBD as instructed as being relatively easy to very easy. However, there was a substantial percentage in the cohort (16%; n = 5) regarding the administration of THC:CBD as inconvenient or very inconvenient.

Demographical and clinical characteristics of the study participants

Subjects who participated in the cohort study met the following inclusion criteria: 1) diagnosis of ALS (ICD-10 G12.2) according to the revised El Escorial criteria [14]; 2) presence of spasticity; 3) treatment with THC:CBD oromucosal spray (Sativex®); 4) consent to participate in the study; 5) participation in a case management program for ALS medication; 6) consent in electronic data capture using a digital research platform [15].

The patient’s treatment satisfaction with THC:CBD, as assessed by Treatment Satisfaction Questionnaire for Medication (TSQM-9). The score was evaluated separately in nine questions, which are as follows. Question 1 (a) – ability of THC:CBD to prevent or treat spasticity: “How satisfied or dissatisfied are you with the ability of THC:CBD to prevent or treat your spasticity?”; Question 2 (b) – the way THC:CBD relieves spasticity: “How satisfied or dissatisfied are you with the way THC:CBD relieves your symptoms?”; Question 3 (c) – amount of time it takes THC:CBD to start working: “How satisfied or dissatisfied are you with the amount of time it takes the medication to start working?”; Question 4 (d) – usability of THC:CBD: “How easy or difficult is it to use the medication in its current form?”; Question 5 (e) – planning when to use THC:CBD: “How easy or difficult is it to plan when you will use the medication each time?”; Question 6 (f) – administration of THC:CBD as instructed: “How convenient or inconvenient is it to take the medication as instructed?”; Question 7 (g) – taking THC:CBD is a good thing: “Overall, how confident are you that taking this medication is a good thing for you?”; Question 8 (h) – the good things about THC:CBD outweigh the bad things: “How satisfied are you that the good things about this medication outweigh the bad things?”; Question 9 (i) – overall satisfaction THC:CBD: “Taking all things into account, how satisfied or dissatisfied are you with this medication”; n = number of patients

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Table 2

Satisfaction with THC:CBD treatment was assessed by means of TSQM-9. This score is a validated assessment scale containing nine questions concerning patients’ satisfaction with medication [22, 23]. TSQM-9 was also validated for the German language [24]. The questions are answered on a five-point or seven-point scale (for example, from very dissatisfied to very satisfied). Each of the nine questions is evaluated in a total score that can range from 0 to 100. A higher total score equates to greater satisfaction. The total score is calculated as follows:

25% of patients (n = 10) received other antispasmodic medication in combination with THC:CBD. Baclofen was used in 25% of patients (n = 10) whereas tizanidine was observed in 5% of studied individuals (n = 2). None of the patients received dantamacrin or botulinum toxin in combination with THC:CBD.

Amyotrophic lateral sclerosis (ALS) is a severe, progressive and incurable neurodegenerative disorder of the upper and lower motor neurons [1, 2]. Patients with predominant upper motor neuron degeneration present with spasticity that is found in 40% of all ALS patients [3]. Spasticity is defined as a velocity-dependent increase in muscle tone in response to an externally imposed stretch or during voluntary movement. Spasticity of the extremities, trunk and bulbar region is associated with central paresis of upper and lower limbs, impaired trunk function, and a pseudobulbar syndrome leading to dysarthria and dysphagia. Beyond the functional effects in mobility, the increase in the muscle tone of spastic muscle groups is perceived as debilitating. It can cause muscle fibrosis, joint contractures, muscle cramps, and pain [4].

Study design

The range of values of the NPS is between positive (+) 100 and negative (−) 100. An NPS with a positive score (greater than zero) is regarded as a supporting recommendation. An NPS of + 50 is considered as excellent [19, 20].

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All observed data including demographic data, clinical characteristics, medication data as well as scales and scores were captured on a digital portal named “APST platform (www.ambulanzpartner.de) [15]. Since all patients were registered on the digital platform, online self-assessment of scales and scores was encouraged. However, due to neurological and psychosocial limitations, online assessment was not possible for all participants. In these cases, the self-assessment data were primarily collected in a telephone interview by the investigator and subsequently captured on the platform.