The term was coined from names of two doctors Adolf Jarisch (1860-1902) and Karl Herxheimer (1861-1942) both of whom noticed that in response to treatment, many patients developed not only fever, perspiration, night sweats, nausea, and vomiting, but their ailments became worse before settling down and healing.
The Herxheimer Effect.
May 16, 2017
What is CBD? 2019
Want to know more about the natural Cannabinoid our body produces? Read our article on Anandamide “the bliss molecule”.
The symptoms of a die-off reaction are generally a worsening of the underlying symptoms of Lyme disease and its associated infections. A majority of Lyme disease symptoms are actually excess inflammatory cytokine symptoms.
In a die-off reaction, there is a release of toxins, proteins, and oxidizing agents that results in an increase in inflammatory cytokines such as tumor necrosis factor-alpha, interleukin-6, and interleukin-8.