Blood coagulation studies were conducted to determine the possible anti-/prothrombotic effect of an organic cannabis extract and the three major cannabinoids, THC, CBD and CBN. The in vitro effect of the cannabis extract on thrombin activity produced an IC50 value of 9.89 mg/ml, compared to THC at 1.79 mg/ml. It was also found that the extract, THC and CBN showed considerable inhibition of thrombin-induced clot formation in vitro with IC50 values of 600, 87 and 83 microg/ml for the extract, THC and CBN respectively. In an in vivo model used to determine clotting times of lean and obese rats treated with a cannabis extract, 50% clotting times were found to be 1.5 and 2 fold greater than their respective control groups, supporting the results obtained in the in vitro model. The study thus shows that Cannabis sativa and the cannabinoids, THC and CBN, display anticoagulant activity and may be useful in the treatment of diseases such as type 2 diabetes in which a hypercoagulable state exists.
Our bodies have a system called the Cytochrome P-450 System which metabolizes toxins in the body. Antibiotics have an effect on this system, and CBD has also been found to inhibit this system. This can have a negative effect because when CBD inhibits the system, it alters the way the system metabolizes other drugs — such as antibiotics. In rare cases, this can lead to overdosing on the antibiotic because your body is not processing the drug properly.
For the past decade or so, CBD oil has been making headlines for its use in treating heart disease to hypertension. Truth be told, it has indeed been shown to be safe, free from side effects, and generally well-tolerated . However, there seems to be ongoing controversy about whether CBD oil can be combined with anticoagulants and blood thinning medications. Does CBD oil thin your blood ? And how safe an option is CBD oil when you are taking blood thinners? Here is everything you need to know.
Keep in mind, however, that this does not happen very often, and most people who take CBD on other medications do not feel any side effects. But it is still a possibility to consider because of the way CBD and antibiotics can interact in your body, which is why it’s so important to consult your doctor before you mix anything with antibiotics or CBD. Additionally, not every antibiotic is the same, which means each one can react differently with CBD.
How to take CBD Oil and Blood Thinners Safely
If you live in a state where cannabis has been decriminalized or legalized, you may have noticed that tons of CBD products are being sold all around you. Cannabidiol (CBD oil) is legal in states with medical marijuana and is extracted from the flowers or buds of marijuana and hemp plants. CBD is not the same thing as the chemical of marijuana THC — THC produces the high many people get from marijuana, whereas CBD is cited for helping with pain, relaxing, sleep, and even skincare. Amazingly, CBD is also being used to prevent seizures and treat epilepsy. The U.S Food and Drug Administration approved CBD medication to treat two rare forms of childhood epilepsy.
There can be adverse effects of taking both CBD and antibiotics regularly, so it’s something you should absolutely ask your medical professional before doing so, just as you would with any other medication you may be taking. They will know what is safe for you based on what medications you’re consuming.
According to a Harvard Medicine School article , CBD can raise the levels of coumadin (a blood thinner aka as heparin or warfarin) in the blood. Nevertheless, studies have shown that this increase of coumadin is done by the very same mechanisms that grapefruit does. That aside, though, the exact interaction between CBD oil and blood clotting is not well understood yet. Nonetheless, some critical factors are believed to come into play, with the impact of CBD oil on blood flow being among the first ones.
CBD and Blood Clotting – The interaction & effects
Several factors, such as your general tolerance, weight, and health can influence your likelihood to experience some side effects or interactions. Given the many variables that need to be considered, it’s strongly recommended to speak to your doctor before taking CBD oil, especially if you’re taking blood thinning medication. Your healthcare practitioner will need to take into account the processing time of CBD oil and make adjustments to your medication so they can safely add it to your medication regimen, with minimal system disruption. In doing so, you may be asked to start with a lower-than-recommended CBD oil dose (to help build a CBD oil tolerance) and gradually increase over time if required.
So the question is, can cbd oil help with pain? Given all these great health benefits, you may be considering buying some products with CBD in them, such as creams and oils. Maybe you want to ingest it to sleep better at night. or you have a chronic illness that causes you a lot of pain. One important thing to be aware of before ingesting anything is to make sure it does not conflict with any other medications you may be taking. So you may be wondering — can you take CBD oil with antibiotics?