cbd for absence seizures

Cbd for absence seizures

Fed: Patient will arrive at the site on Day 1 of Week 4 of the Treatment Period without food and the morning dose. Site will provide a high fat/high calorie food then doses patient. Blood samples will be collected pre-dose (before meal/morning dose) and 2, 4, 6 hours after the morning dose (but before next dose).

Treatment Period: Cannabidiol Oral Solution 40 mg/kg/day divided BID for 4 weeks.

Treatment Period: Cannabidiol Oral Solution 30 mg/kg/day divided BID for 4 weeks.

Fed: Patient will arrive at the site on Day 1 of Week 4 of the Treatment Period without food and the morning dose. Site will provide a high fat/high calorie food then doses patient. Blood samples will be collected pre-dose (before meal/morning dose) and 2, 4, 6 hours after the morning dose (but before next dose).

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Titration Period: Cannabidiol Oral Solution 20 mg/kg/day divided BID for 5 days.

Resource links provided by the National Library of Medicine

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Cbd for absence seizures

T he first time Evelyn and I talked about cannabis as a treatment for epilepsy was in early June 2011. The high-fat diet Sam had been on for two years had stopped working. There were no more conventional antiepileptic drugs to try. In our scramble to find solutions, Evelyn learned that a nurse-practitioner in one of our doctors’ offices was starting a cannabis collective—outside of work—to help some of the physician’s sickest kids. Other parents of epileptic kids we knew were joining. Besides having a medical degree, the nurse was an herbalist. She’d heard that cannabis—if made into oil-based tinctures, taken by the drop instead of smoked—could help people with intractable seizures.Evelyn liked the fact that the nurse sent her a 1981 paper from The Journal of Clinical Pharmacology on cannabinoids as potential antiepileptics. And she liked that the nurse assured her that the cannabis being used wouldn’t get anyone stoned. It would be high in CBD and low in THC.

My first reaction to the idea of trying cannabis to treat Sam was that it sounded crazy. I’d smoked plenty of weed in college and in my twenties. I knew the plant could have real medicinal effects; medical cannabis was legal to buy in California with proper documentation. But rightly or wrongly, the idea of controlling Sam’s seizures with cannabis—he was 10 at the time—alarmed me. I associated pot with partying, not treating my son’s serious illness. I hated having the two thoughts side by side.

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An article in a medical journal led Evelyn, Sam’s mom, to reach out to a British drug company that makes cannabis-based medicine. Elinor Carucci

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Sam would be the first kid, and arguably the first person in more than 20 years, to try pharmaceutical-grade CBD as a treatment for epilepsy.