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The pH of bodily fluids, such as saliva and urine, does change temporarily depending on the foods you eat, but that doesn’t affect blood pH levels (or, hence, the environment of cancer cells in the body). In fact, any significant deviation in blood pH levels can cause serious, even life-threatening conditions known as acidosis (low pH) or alkalosis (high pH)

The verdict: “So far, there are no human studies that show cannabis oil can be used as cancer treatment,” Dr. Yeung says. “Patients who are using it — or any form of marijuana — should let their doctors know so they can advise you properly.”

The evidence: Cancer cells create an acidic microenvironment due to a high metabolic rate. Cancer cells can’t live in a highly alkaline environment, but neither can healthy cells. Your body works to keep pH levels constant, and changing your diet is not going to substantially change the pH levels of your blood, which are tightly regulated by the kidneys and lungs regardless of foods consumed.

Dr. Yeung is manager of the About Herbs database, created and maintained by MSK’s Integrative Medicine Service. The service provides complementary therapies such as acupuncture, music therapy, and massage that are used in addition to — not as alternatives for — mainstream cancer approaches such as chemotherapy, radiation, and surgery.

Manipulating pH Levels through Diet

The hype: Based on the scientific observation that cancer cells thrive in an acidic environment — meaning low pH levels — some people contend that highly “acidic” foods such as meat, cheese, and grain products raise the risk of cancer by reducing pH levels in the blood. They claim that eating “alkaline” foods such as fruit, green vegetables, and other plant-based products discourages the growth of cancer cells by raising blood pH levels and tout the benefits of the alkaline diet (also known as the alkaline ash diet or alkaline acid diet).

The hype: Laetrile, first popularized as a cancer therapy in Russia and the United States more than a century ago, is the trade name for a purified form of amygdalin, an extract derived from apricot pits and some nuts and plants. Intestinal enzymes break down Laetrile to produce cyanide, which proponents claim kills cancer cells and leaves normal tissue unharmed. Some also claim that Laetrile is actually a vitamin called B-17 and that deficiencies can cause certain cancers. Banned in the United States, an oral form of Laetrile is available in other countries.

The verdict: “There is no evidence that changing your diet to alter pH levels affects cancer growth,” Dr. Yeung says. “The actual science has been misinterpreted. Changing the pH in your saliva doesn’t mean your blood pH changes. Some patients try using chemicals to modify their blood pH, but that can be extremely dangerous.”

Laetrile

Claims that cannabis oil cures cancer are anecdotal and largely unsupportable, based on scant research done in mice and in labs. Side effects can include memory and attention loss. Perhaps most important, there is evidence that cannabis compounds may inhibit enzymes that patients need to metabolize other anticancer drugs, thereby increasing their toxicity or reducing their effectiveness.

Here, Dr. Yeung explains the hype and the scientific evidence surrounding three highly publicized but unproven therapies: cannabis oil, Laetrile, and a pH-manipulation (also known as alkaline) diet.

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