Can You Take CBD Oil With Cymbalta


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Contributor: Dr. Augustine Provencio, MD CBD and Cymbalta explained. When finding treatment for common illnesses like chronic pain and anxiety, the search Your access to this site has been limited by the site owner If you think you have been blocked in error, contact the owner of this site for assistance. If you are a WordPress user with There is little research into the interaction between Cymbalta and cannabis, but there may be one if the two are used together.

CBD and Cymbalta

CBD and Cymbalta explained. When finding treatment for common illnesses like chronic pain and anxiety, the search for a substance that works can be frustrating to patients, and in cases, worsen already existing side effects.

Cymbalta, also known as Duloxetine, is a prescription medication used to treat symptoms of anxiety, depression, and Fibromyalgia. CBD, another well know substance, is paving the way as a new revolutionary drug to help treat a variety of diseases. Here we will discuss CBD and its reaction / potential side effects when mixed with Cymbalta.

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What Does Cymbalta Treat

Anxiety and depression affect the sufferers physical and emotional responses to stressors and stimuli, often creating negative (and in many cases involuntary) responses to seemingly insignificant triggers. Fibromyalgia, or a tight pain in muscles and pressure points throughout the body, can be both caused by and cause anxiety-like symptoms.

Why Compare Cymbalta and CBD

Some patients using Cymbalta have begun to look to CBD as a method of increasing the positive effects of the drug such as pain and anxiety relief, or in other cases hope that the addition of CBD will make it possible to lower or change their Cymbalta dosage with less harsh side effects. Navigating the dosage and alteration of treatment can be tricky, which has raised questions of just how effective CBD is in relation to Cymbalta and whether or not pairing the two is a safe choice. CBD has been observed to help patients with both anxiety and pain, prompting closer examination of the interactions CBD can have with Cymbalta.

How Does Cymbalta Work Chemically

Cymbalta, similar to CBD, interacts with the Serotonin centers in the brain. Cymbalta is a serotonin-norepinephrine reuptake inhibitor. The delayed release capsules stimulate serotonin centers which help to create a calming effect and elevate mood. Specifically, Cymbalta prevents brain cells from quickly absorbing neurotransmitters and sending overactive messages of panic and fear to the body known as fight or flight responses. These responses include symptoms of both anxiety and Fibromyalgia. Muscle pain and tension typical to Fibromyalgia sufferers can be brought about by panic attacks.

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How Does CBD Work Chemically

CBD functions in a similar way to Cymbalta, working with receptors that trigger fear responses and bodily reactions (muscle tension, headaches etc.) By interacting with the parts of the brain responsible for symptoms of anxiety and Fibromyalgia, substances like Cymbalta can lessen the severity of these symptoms. Many CBD users have have reported to notice relief for these same symptoms from using CBD oil.

Possible Side Effects of Cymbalta

A major concern in mixing CBD and Cymbalta is how CBD can exasperate already possible negative side effects. Side effects largely depend on the individual patient, their chemical makeup, and what Cymbalta is prescribed to them for. These side effects include:

  • Nusea
  • Dry Mouth
  • Fatigue
  • Loss of Appetite
  • Sweating
  • Increased anxiety or panic attacks
  • Increased depression
  • Suicidal thoughts

Other Cymbalta Concerns

Some patients prescribed Cymbalta have reported withdrawal symptoms after stopping the medication. This reaction is not uncommon after discontinuation of depression and anxiety medications, which is another strong reason that some patients have begun to try CBD. CBD oil can help with withdrawal effects while presenting no withdrawal effects of its own. Read more about patients reports on Cymbalta withdraws here.

How Do CBD and Cymbalta Interact

Some observations have noticed moderate interaction between CBD / Cannabis products and Cymbalta. While there are no fatal or extremely internally hazardous interactions noted to date, CBD and Cymbalta can cause complications when used together for the treatment of anxiety or chronic pain. Among these interactions are:

  • Dizziness
  • Confusion
  • Lack of Concentration
  • Impaired Judgement
  • Loss of memory

These symptoms are noted to be worse in elderly users.

Mixing Cymbalta and CBD

In terms of mixing CBD and Cymbalta for anxiety, it may be helpful for cases of insomnia (or sleeplessness brought on by moderate to severe pain) but presents risks for users when functioning through normal daily activities. CBD and Cymbalta together present largely sedative interactions.

Studies of CBD and Fibromyalgia

Fibromyalgia is one of the main ailments Cymbalta is prescribed for. Though CBD and Cymbalta are not extremely beneficial together, patients concerned about potential withdrawal from Cymbalta do have the option of turning to CBD as an alternative medication. A recent study tested cannabis products against three Fibromyalgia medications including Cymbalta and found that 62% of patients tested found CBD to be a helpful treatment for chronic pain.

CBD as Long-term Pain Relief Alternative

Other patients who have not found relief in major FDA approved drugs have reported some positive findings when using CBD to tried their Fibromyalgia related pain. One user expressed that she did feel significant relief after years of searching, but did warn that buyers should closely monior the quality of the CBD they buy. Good CBD may be more expensive, but when taking the place of a larger drug like Cymbalta, the cost was worth it.

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Taking CBD with Cymbalta has not been observed to have inherently lethal or harmful side effects, however, some of the side effects noted can make it difficult to perform daily tasks like driving, operating machinery, and making decisions. These interactions have been especially prominent in elderly users. When compared to Cymbalta as a treatment option for Fibromyalgia, users have found proportionately positive results. CBD offers a treatment that has been observed to be effective in treating pain while avoiding the difficult withdrawal symptoms some Cymbalta users have suffered.

How to Try Safely

Before making any changes to your treatment for anxiety, depression, or Fibromyalgia, it is important to consult your doctor and make your interest in CBD as an alternative known. Only a medical professional can properly help in balancing dosages and alerting you to and possible adverse reactions you may not have been aware of. As with any medication, figuring out the exact dose and frequency that will be most effective for your symptoms may take time, and communicating your goals, experiences, and preferences clearly with your doctor. As more studies are conducted on CBD as a treatment option, more possibilities become clear. If you have found little relief from taking Cymbalta, or are looking to make a change with less withdrawal symptoms, CBD may be an option to consider.

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Should You Use Marijuana If You Take Cymbalta?

Cymbalta is a prescription medication used to soothe several medical conditions, such as anxiety, depression and chronic pain. Many of these symptoms are among the approved uses for medical marijuana in legalized states.

While a sizable amount of research explores cannabis’ connection with psychiatric disorders, there’s little that examines antidepressants like Cymbalta’s interaction with marijuana. Some sources suggest that Cymbalta (duloxetine) has a moderate drug-drug interaction with cannabis, potentially interfering with its metabolization by the liver.

Download Guide To Anxiety and Medical Cannabis
Download Free Guide to Marijuana and Chronic Pain

What Is Cymbalta?

Cymbalta — generically called duloxetine —‚ is one of the selective serotonin-norepinephrine reuptake inhibitors (SSNRIs) that increases the levels of serotonin and norepinephrine in the brain. These chemicals influence mood and pain sensations, and taking Cymbalta helps regulate them when their levels are imbalanced.

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Side effects of Cymbalta range in severity and include:

Uses and How It Works

SNRIs are a newer class of antidepressants that have shown a more promising ability to regulate mood without the traditional adverse effects of SSRIs like Prozac. Medications like Cymbalta work by modulating the neurotransmitters in the brain that communicate information between brain cells. By preventing the reuptake of serotonin and norepinephrine in the brain, Cymbalta can lift patients out of depression and soothe experiences of pain.

Potential Benefits and Risks of Mixing Cannabis and Cymbalta

Potential Benefits

We do not yet know if cannabis interacts with Cymbalta. Current research implicates marijuana as a promising aid to treat various conditions, including several disorders doctors prescribe Cymbalta to treat. As such, medical marijuana may offer an alternative for individuals who cannot or choose not to take SNRIs.

Evidence suggests that individuals who regularly use medical marijuana experience less depression. CBD, too, counteracts many of the adverse effects of THC’s psychoactivity, which could worsen anxiety with too high a dose. However, CBD is known to interact with many medications due to its impact on metabolic activity in the liver. Be sure to discuss using cannabis and Cymbalta with your doctor before making any changes to your medication routine.

CBG is another promising cannabinoid that could boost the antidepressant ability of Cymbalta. It works by preventing the reuptake of GABA, which contributes to a sense of peace and calm using a different neural pathway than SNRIs.

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Potential Risks

While marijuana use and Cymbalta produce many of the same results, users should exercise caution before taking them simultaneously. Cannabis use with Cymbalta could impair cognitive and motor function, making it more difficult to focus or complete tasks.

Additionally, some of marijuana and Cymbalta’s side effects are similar, which could magnify these experiences if the drugs are taken in tandem. Both cannabis and Cymbalta display central nervous system (CNS) depressant properties, which can dangerously reduce heart rate and breathing when too much is taken.

The Bottom Line

There’s still much to learn about mixing cannabis with Cymbalta or other SRNIs; each person’s body handles drugs differently. Always discuss potential changes to your prescription routine with a medical professional before taking action, as a doctor should be able to answer most questions.

Leafwell’s dedicated team of medical professionals is here to guide you through applying for your MMJ card online.

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