adverse effects of cbd

Adverse effects of cbd

Cannabidiol (CBD) is often covered in the media, and you may see it touted as an add-in booster to your post-workout smoothie or morning coffee. You can even buy a CBD-infused sports bra. But what exactly is CBD? And why is it so popular?

How is cannabidiol different from marijuana, cannabis and hemp?

Animal studies, and self-reports or research in humans, suggest CBD may also help with:

The evidence for cannabidiol health benefits

CBD, or cannabidiol, is the second most prevalent active ingredient in cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, a cousin of marijuana, or manufactured in a laboratory. One of hundreds of components in marijuana, CBD does not cause a “high” by itself. According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”

It's important to point out that CBD is not regulated by the FDA and therefore dosages might not be accurate. It’s also difficult to know what an appropriate dose is the first time you try a new product.

“Since discovering the endocannabinoid system (ECS) in the body in the 1990s, CBD has been researched more extensively. The ECS is a central regulatory system restoring normal balance and homeostasis in a range of human physiologic systems throughout the body and brain and has cannabinoid receptors and chemicals in its function,” explains Dr. Matharu-Daley.

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Because CBD supplements come in so many different forms—such as oils, gummies, tinctures, and vapors—the amount that’s actually absorbed can vary drastically. This, combined with each person, will ultimately affect which (if any) CBD side effects you might experience.

Ultimately, the primary reasons why people use CBD is because it tends to have calming, relaxing, pain-reducing effects. It has been used to alleviate joint pain and nerve pain, reduce anxiety and stress, treat insomnia, improve migraines, and address nausea.

Are There Any Benefits Associated With Using CBD?

CBD benefits include the following:

“CBD is not an intoxicating substance, whereas THC is a psychoactive that can get you high,” explains Dr. Jas Matharu-Daley, a physician and consultant for a brand that specializes in CBD production.

The most comment side effects of CBD include drowsiness, gastrointestinal issues, dry mouth, reduced appetite, nausea, and interaction with other medications. Those are outlined in detail below.

What Is Cannabidiol (CBD)?

CBD is one of the many chemical compounds that is found in the cannabis plant—referred to as cannabis sativa. There are two primary parts of the plant that humans use. One is THC, or Delta-9-Tetrahydrocannabinol, and the other is CBD. Though they’re from the same plant, THC and CBD are quite different from each other.

CBD might interfere with the other medications you take. Dr. Matharu-Daley says it’s important to talk to your doctor about whether CBD could affect your existing prescriptions.

Adverse effects of cbd

Outside of these two disorders, CBD's effectiveness in treating seizures is uncertain. Even with Epidiolex, it's unclear if the anti-seizure effects are from CBD or some other factor.

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Instead, CBD influences other receptors, like the opioid receptors that control pain. It also affects glycine receptors. These control serotonin, a brain chemical known as the “feel-good” hormone.

Remember that CBD oils are mostly unregulated, so there's no guarantee that a product is safe, effective, or what it claims to be on its packaging.

Interactions

Cytochrome P450 (CYP450) is an enzyme in your body that breaks down certain drugs. But CBD oil can block CYP450 from working the way it normally does. CBD oil can either make some drugs you take have a stronger effect than you need or make them less effective.

There aren't many study trials that look at CBD's anxiety-relieving effects in humans. One of the few is a 2019 study published in the Brazilian Journal of Psychiatry.

Anxiety

Drugs that could potentially interact with CBD include:

Clinical research has shown that CBD oil can trigger side effects. The severity and type can vary from one person to the next.